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New England Journal of Medicine (NEJM) Audio Summaries

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NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 1.

This summary covers the issue of July 2, 2009. Featured are articles on phospholipase A2 receptor in idiopathic membranous nephropathy, an epidemiologic study of in-hospital CPR in the elderly, preoperative staging of lung cancer with combined PET-CT, the effects of enalapril and losartan in type 1 diabetes, the effect of Medicare Part D on drug and medical spending, and cardiomyocyte renewal; a review article on rhabdomyolysis and acute kidney injury; a Clinical Problem-Solving article describ...

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[ Wed, 1 Jul 2009 10:18:14 -0400 ]

NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 26.

This summary covers the issue of June 25, 2009. Featured are articles on routine early angioplasty after fibrinolysis for acute myocardial infarction, mutation in ovarian granulosa-cell tumors, treating childhood acute lymphoblastic leukemia without cranial irradiation, and isolated familial hypogonadotropic hypogonadism and a GNRH1 mutation; review articles on alpha1-antitrypsin deficiency and on alcoholic hepatitis; a case report of a woman with a blistering cutaneous eruption; and Perspectiv...

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[ Wed, 24 Jun 2009 10:18:14 -0400 ]

NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 25.

This summary covers the issue of June 18, 2009. Featured are articles on the emergence of a novel swine-origin influenza A (H1N1) virus in humans, triple-reassortant swine influenza A (H1) in humans in the United States, 2005-2009, evaluation of universal antenatal screening for group B streptococcus, immunodeficiency associated with FCN3 mutation and ficolin-3 deficiency, and a new target for tumor therapy; a review article on autologous hematopoietic stem-cell transplantation for multiple mye...

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[ Wed, 17 Jun 2009 10:18:14 -0400 ]

NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 24.

This summary covers the issue of June 11, 2009. Featured are articles on treatment for type 2 diabetes and coronary artery disease, duration of androgen suppression in the treatment of prostate cancer, safety of metaclopramide use in the first trimester of pregnancy, Zika virus outbreak on Yap Island, and primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants; a review article on prenatal screening for aneuploidy; a Clinical Problem-Solving article entitled Kiss of Death; an...

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[ Wed, 10 Jun 2009 10:18:14 -0400 ]

NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 23.

This summary covers the issue of June 4, 2009. Featured are articles on diarylquinoline TMC207 for MDR tuberculosis, overseas screening for tuberculosis in U.S.-bound immigrants and refugees, canakinumab in the cryopyrin-associated periodic syndrome, an autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist, an autoinflammatory disease due to homozygous deletion of the IL1RN locus, and the granuloma in tuberculosis; a review article on immunologic aspects of COPD; a c...

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[ Wed, 3 Jun 2009 10:18:14 -0400 ]

NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 22.

This summary covers the issue of May 28, 2009. Featured are articles on radiofrequency ablation in Barrett's esophagus with dysplasia; mutation in TET2 in myeloid cancers; age, neuropathology, and dementia; inactivating PAPSS2 mutations in a patient with premature pubarche; and handguns, health, and the Second Amendment; review articles on chronic venous insufficiency and varicose veins and on predisposing factors for adrenal insufficiency; a case report of a man with progressive neurologic def...

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[ Wed, 27 May 2009 10:18:14 -0400 ]

NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 21.

This summary covers the issue of May 21, 2009. Featured are articles on early versus delayed invasive intervention in acute coronary syndromes, early glycoprotein IIb/IIIa inhibition in acute coronary syndromes, dipyridamole plus aspirin for hemodialysis graft patency, cost implications of reduced work hours and workloads for resident physicians, and mining rhinovirus sequencing; a review article on fomepizole for ethylene glycol and methanol poisoning; a case report of a pregnant woman with an...

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[ Wed, 20 May 2009 10:18:14 -0400 ]

NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 20.

This summary covers the issue of May 14, 2009. Featured are articles on adjuvant chemotherapy in older women with early-stage breast cancer, effect of clopidogrel added to aspirin in patients with atrial fibrillation, epinephrine and dexamethasone in children with bronchiolitis, antivenom for critically ill children with neurotoxicity from scorpion stings, and a fatal case of deer tick encephalitis; a review article on fungal nail disease; a case report of a man with coma after cardiac arrest; ...

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[ Wed, 13 May 2009 10:18:14 -0400 ]

NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 19.

This summary covers the issue of May 7, 2009. Featured are articles on long-term safety and efficacy of drug-eluting versus bare-metal stents in Sweden; paclitaxel-eluting stents versus bare-metal stents in acute myocardial infarction; epilepsy, ataxia, sensorineural deafness, tubulopathy, and KCNJ10 mutations; STIM1 mutation associated with a syndrome of immunodeficiency and autoimmunity; vaccine refusal and the risks of vaccine-preventable diseases; New York City's war on fat, and the origins...

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[ Wed, 6 May 2009 10:18:14 -0400 ]

NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 18.

This summary covers the issue of April 30, 2009. Featured are articles on CD4 count and antiretroviral therapy for HIV, telaprevir with peginterferon and ribavirin for chronic HCV infection, telaprevir and peginterferon with or without ribavirin for chronic HCV infection, rosuvastatin to prevent venous thromboembolism; review articles on asthma in pregnancy and on aspergillosis; a case report of a man with chest pain, dysphagia, and pleural and mediastinal calcifications; and Perspective articl...

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[ Wed, 29 Apr 2009 10:18:14 -0400 ]

NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 17.

This summary covers the issue of April 23, 2009. Featured are articles on coronary bypass surgery with or without surgical ventricular reconstruction, susceptibility locus for stroke, HTRA1 mutations and familial ischemic cerebral small-vessel disease, changes in the incidence and duration of periods without insurance, and autophagy and Crohn's disease; review articles on minimally invasive total knee arthroplasty and on understanding genetic causes of disease; a case report of a woman with res...

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[ Wed, 22 Apr 2009 10:18:14 -0400 ]

NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 16.

This summary covers the issue of April 16, 2009. Featured are articles on cognitive function at 3 years of age after fetal exposure to antiepileptic drugs, valsartan for prevention of recurrent atrial fibrillation, inhibitors of factor VIII in black patients with hemophilia, and electronic health records in U.S. hospitals; review articles on molar pregnancy and on genetics of type 1A diabetes; a case report of a man with migraine, aphasia, and hemiparesis and similarly affected family members; ...

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[ Wed, 15 Apr 2009 10:18:14 -0400 ]

NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 15.

This summary covers the issue of April 9, 2009. Featured are articles on efficacy of esomeprazole for treatment of poorly controlled asthma, brown adipose tissue in healthy adults, shifting terrain in the regulation of off-label promotion of pharmaceuticals, and fibrosis and myocardial infarction; a review article on myocarditis; a case report of a man with fever, headache, rash, and vomiting; and Perspective articles on stimulating the adoption of health information technology, on the NIH stim...

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[ Wed, 8 Apr 2009 10:18:14 -0400 ]

NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 14.

This summary covers the issue of April 2, 2009. Featured are articles on cervical cancer in rural India, rosuvastatin and cardiovascular events in hemodialysis patients, cetuximab and chemotherapy for metastatic colorectal cancer, and rehospitalizations among Medicare patients; review articles on enuresis and on medical evaluation of patients undergoing electroconvulsive therapy; a Clinical Problem-Solving article describing a question well put; and Perspective articles on a to-do list for the ...

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[ Wed, 1 Apr 2009 10:18:14 -0400 ]

NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 13.

This summary covers the issue of March 26, 2009. Featured are articles on intensive vs. conventional glucose control in critically ill patients, circumcision to prevent HSV-2 and HPV infections and syphilis, mortality results from a randomized prostate-cancer screening trial, screening and prostate-cancer mortality in a randomized European study, and maternal influence on fetal immunity; a review article on pulmonary rehabilitation for management of chronic obstructive pulmonary disease; a case...

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[ Wed, 25 Mar 2009 10:18:14 -0400 ]

NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 12.

This summary covers the issue of March 19, 2009. Featured are articles on racial differences in heart failure in young adults, vaccine prevention of maternal cytomegalovirus infection, genetic association with ovarian insufficiency, and genetic compensation in a human genomic disorder; review articles on carbon monoxide poisoning and on moyamoya disease; a case report of a man with massive rectal bleeding; and Perspective articles on the uncertain future for cardiovascular drug development, on ...

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[ Wed, 18 Mar 2009 10:18:14 -0400 ]

NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 11.

This summary covers the issue of March 12, 2009. Featured are articles on melamine-contaminated powdered formula and urolithiasis in young children; a test for arrhythmogenic right ventricular cardiomyopathy; long-term ozone exposure and mortality; a nonsimultaneous, extended altruistic-donor chain; growth in the care of older patients by hospitalists in the United States; and reversing artherosclerosis; a review article on primary open-angle glaucoma; a case report of a woman with headache, hyp...

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[ Wed, 11 Mar 2009 10:18:14 -0400 ]

NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 10.

This summary covers the issue of March 5, 2009. Featured are articles on PCI vs. CABG for severe coronary artery disease, mepolizumab and corticosteroid-resistant asthma, and health insurers and medical-imaging policy; review articles on Graves' ophthalmopathy and on asthma; a Clinical Problem-Solving article describing a case in which past is prologue; and Perspective articles on coming to grips with foodborne infection, on global transmission of oseltamivir-resistant influenza, and on seroton...

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[ Wed, 4 Mar 2009 10:18:14 -0500 ]

NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 9.

This summary covers the issue of February 26, 2009. Featured are articles on a comparison of weight-loss diets with different compositions of fat, protein, and carbohydrates, C3 polymorphisms and allograft outcome in renal transplantation, spermatogenesis in a man with complete deletion of USP9Y, emergence of ciprofloxacin-resistant Neisseria meningitidis in North America, and acute promyelocytic leukemia; review articles on excision and grafting of thermal burns and on preservation of fertilit...

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[ Wed, 25 Feb 2009 10:18:14 -0500 ]

NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 8.

This summary covers the issue of February 19, 2009. Featured are articles on estimation of warfarin dose, IDH1 and IDH2 mutations in gliomas, quality of life after late invasive therapy for occluded arteries, implications of the globalization of clinical research, and progress and deficiencies in the registration of clinical trials; review articles on epistaxis and on gene-expression signatures in breast cancer; a case report of a woman with vertigo, facial weakness, and a generalized seizure; ...

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[ Wed, 18 Feb 2009 10:18:14 -0500 ]

NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 7.

This summary covers the issue of February 12, 2009. Featured are articles on B-cell clones as early markers for chronic lymphocytic leukemia, effect of dronedarone on cardiovascular events in atrial fibrillation, endocrine therapy plus zoledronic acid in premenopausal breast cancer, long-term control of HIV by CCR5 Delta 32/Delta 32 stem-cell transplantation, financial incentives for smoking cessation, and stress and inflammatory bowel disease; a case report of a woman with a rash and numbness a...

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[ Wed, 11 Feb 2009 10:18:14 -0500 ]

NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 6.

This summary covers the issue of February 5, 2009. Featured are articles on chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer, breast cancer after estrogen plus progestin in postmenopausal women, respiratory syncytial virus infection in young children, mutations in SYNGAP1 in autosomal nonsyndromic mental retardation, and limits on Medicare's ability to control spending on cancer drugs; a review article on primary ovarian insufficiency; a Clinical Problem-Solving article ...

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[ Wed, 4 Feb 2009 10:18:14 -0500 ]

NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 5.

This summary covers the issue of January 29, 2009. Featured are articles on gene therapy for immunodeficiency due to adenosine deaminase deficiency, long-term consequences of kidney donation, deletion of IKZF1 and prognosis in acute lymphoblastic leukemia, weight loss to treat urinary incontinence in overweight and obese women, a surgical safety checklist to reduce morbidity and mortality in a global population, and a proteomic analysis of ischemic preconditioning; a review article on behaviora...

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[ Wed, 28 Jan 2009 10:18:14 -0500 ]

NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 4.

This summary covers the issue of January 22, 2009. Featured are articles on oral prednisolone for preschool children with acute virus-induced wheezing, preemptive high-dose fluticasone for virus-induced wheezing in children, cytochrome P-450 polymorphisms and response to clopidogrel, genetic determinants of response to clopidogrel and cardiovascular events, and fine-particulate air pollution and life expectancy in the United States; a review article on seborrheic dermatitis; a case report of a ...

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[ Wed, 21 Jan 2009 10:18:14 -0500 ]

NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 3.

This summary covers the issue of January 15, 2009. Featured are articles on fractional flow reserve versus angiography for guiding percutaneous coronary intervention, atypical antipsychotic drugs and the risk of sudden cardiac death, cumulative live-birth rates after in vitro fertilization, effect of pneumococcal conjugate vaccine on pneumococcal meningitis, peginterferon alfa-2a and ribavirin in Latino and non-Latino whites with hepatitis C, and oncogenesis and metastasis; a review article on ...

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[ Wed, 14 Jan 2009 10:18:14 -0500 ]

NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 2.

This summary covers the issue of January 8, 2009. Featured are articles on timing of elective repeat cesarean delivery and neonatal outcomes, a strategy to control transmission of Schistosoma japonicum in China, glucose control and vascular complications in type 2 diabetes, arterial blood gases and oxygen content in climbers on Mount Everest, and mortality attributable to smoking in China; a review article on vitiligo; a case report of a man with progressive cognitive decline; and Perspective a...

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[ Wed, 7 Jan 2009 10:18:14 -0500 ]

NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 1.

This summary covers the issue of January 1, 2009. Featured are articles on machine perfusion or cold storage in deceased-donor kidney transplantation, decontamination of the digestive tract and oropharynx in ICU patients, a syndrome with congenital neutropenia and mutations in G6PC3, modulation of blood pressure by central melanocortinergic pathways, giant osteoclast formation and long-term oral bisphosphonate therapy, and bacterial virulence and the living system; a review article on radiation...

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[ Wed, 31 Dec 2008 10:18:14 -0500 ]

NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 359, No. 26.

This summary covers the issue of December 25, 2008. Featured are articles on cognitive behavioral therapy and sertraline in childhood anxiety, genetic variants in diabetes and celiac disease, inhibition of the Bcl-xL deamidation pathway in myeloproliferative disorders, azathioprine or methotrexate maintenance for ANCA-associated vasculitis; review articles on acute pulmonary embolism and on the molecular basis of metastasis; a case report of a man with blurred vision; and Perspective articles o...

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[ Wed, 24 Dec 2008 10:18:14 -0500 ]

NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 359, No. 25.

This summary covers the issue of December 18, 2008. Featured are articles on Dicer, Drosha, and outcomes in ovarian cancer, thrombolysis during resuscitation for out-of-hospital cardiac arrest, alfuzosin in chronic prostatitis-chronic pelvic pain syndrome, adverse reactions associated with contaminated heparin, PHD2 mutation and congenital erythrocytosis with paraganglioma, and boosting beta-cell numbers; a review article on temporomandibular disorders; a case report of a woman with splenomegal...

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[ Wed, 17 Dec 2008 10:18:14 -0500 ]

NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 359, No. 24.

This summary covers the issue of December 11, 2008. Featured are articles on the efficacy of RTS,S/AS01E vaccine against malaria in children 5 to 17 months of age, safety and immunogenicity of RTS,S/AS02D malaria vaccine in infants, combination antimalarial therapies in children, an obesity-associated FTO gene variant and increased energy intake in children, effect of aspirin or resistant starch on hereditary colorectal neoplasia; a review article on the prevention and treatment of seasonal inf...

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[ Wed, 10 Dec 2008 10:18:14 -0500 ]

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