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New England Journal of Medicine (NEJM) Audio Summaries

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NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 20.

This summary covers the issue of November 12, 2009. Featured are articles on critical care services and 2009 H1N1 influenza in Australia and New Zealand; hospitalized patients with 2009 H1N1 influenza in the United States, April-June; cross-reactive antibody responses to the 2009 pandemic H1N1 influenza virus, revascularization versus medical therapy for renal-artery stenosis, and outcome reporting in industry-sponsored trials of gabapentin for off-label use; a review article on renal-artery st...

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[ Wed, 11 Nov 2009 10:18:14 -0400 ]



NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 19.

This summary covers the issue of November 5, 2009. Featured are articles on on-pump versus off-pump CABG, vaccination against HPV-16 oncoproteins for vulvar intraepithelial neoplasia, a peptide-based erythropoietin-receptor agonist for pure red-cell aplasia, testosterone and spermatogenesis, and figuring out ferroportin; review articles on phosphodiesterase type 5 inhibitors for pulmonary arterial hypertension and on myelodysplastic syndromes; a Clinical Problem-Solving article describing a blo...

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[ Wed, 4 Nov 2009 10:18:14 -0400 ]



NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 18.

This summary covers the issue of October 29, 2009. Featured are articles on the association between susceptibility to fungal infections and a mutation in CARD9, three-year efficacy of complex insulin regimens in type 2 diabetes, antibiotic prophylaxis and recurrent urinary tract infection in children, and human dectin-1 deficiency and mucocutaneous fungal infections; review articles on postexposure prophylaxis for HIV infection and on norovirus gastroenteritis; a case report of a man with sore ...

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[ Wed, 28 Oct 2009 10:18:14 -0400 ]



NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 17.

This summary covers the issue of October 22, 2009. Featured are articles on intensity of continuous renal-replacement therapy in critically ill patients, strict blood-pressure control and progression of renal failure in children, glucocerebrosidase mutations in Parkinson’s disease, cisplatin versus cisplatin plus doxorubicin for standard-risk hepatoblastoma, X-linked thrombophilia with a mutant factor IX, and probing prostate cancer; a review article on atypical hemolytic–uremic synd...

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[ Wed, 21 Oct 2009 10:18:14 -0400 ]



NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 16.

This summary covers the issue of October 15, 2009. Featured are articles on the clinical course of advanced dementia, functional status of elderly adults before and after initiation of dialysis, interleukin-2 therapy in patients with HIV infection, and the benefits of taxing sugar-sweetened beverages; review articles on bacterial diarrhea and on cell death; a case report of a man with progressive dyspnea; and Perspective articles on controlling expenditures by improving care for patients needin...

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[ Wed, 14 Oct 2009 10:18:14 -0400 ]



NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 15.

This summary covers the issue of October 8, 2009. Featured are articles on defibrillator implantation early after myocardial infarction, microRNA expression, survival, and response to interferon in liver cancer, doxycycline for Mansonella perstans infection, osteoporosis associated with neutralizing autoantibodies against osteoprotegerin, accuracy of conflict-of-interest statements, and gray-matter injury in multiple sclerosis; a review article on DNA damage, aging, and cancer; a case report of...

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[ Wed, 7 Oct 2009 10:18:14 -0400 ]



NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 14.

This summary covers the issue of October 1, 2009. Featured are articles on cardiac-resynchronization therapy for the prevention of heart-failure events, a multicenter, randomized trial of treatment for mild gestational diabetes, moderate hypothermia for perinatal asphyxial encephalopathy, recurrence of bile salt export pump deficiency after liver transplantation, variation in hospital mortality associated with inpatient surgery, and balancing "no blame" with accountability in patient safety; a ...

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[ Wed, 30 Sep 2009 10:18:14 -0400 ]



NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 13.

This summary covers the issue of September 24, 2009. Featured are articles on daunorubicin for acute myeloid leukemia in older patients, anthracycline dose intensification in AML, comparative efficacy of inactivated and live attenuated influenza vaccines, a double-blind, delayed-start trial of rasagiline in Parkinson's disease, the delayed-start study design, interferon-alpha; and the treatment of leukemia; a review article on renal failure in cirrhosis; a case report of a man with recurrent tr...

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[ Wed, 23 Sep 2009 10:18:14 -0400 ]



NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 12.

This summary covers the issue of September 17, 2009. Featured are articles on dabigatran versus warfarin in patients with atrial fibrillation, sex hormone-binding globulin and risk of type 2 diabetes in women and men, inhibition of the hedgehog pathway in advanced basal-cell carcinoma, treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449, and Congress, the FDA, and drug-regulation preemption; a review article on screening for colorectal cancer; a case report of a man with weight...

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[ Wed, 16 Sep 2009 10:18:14 -0400 ]



NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 11.

This summary covers the issue of September 10, 2009. Featured are articles on ticagrelor versus clopidogrel in patients with acute coronary syndromes, recurring mutations in acute myeloid leukemia, asymptomatic reactivation of JC virus in patients treated with natalizumab, treatment of progressive multifocal leukoencephalopathy associated with natalizumab, PML after natalizumab monotherapy, and understanding abdominal aortic aneurysm; a review article on parenteral nutrition in the critically i...

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[ Wed, 9 Sep 2009 10:18:14 -0400 ]



NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 10.

This summary covers the issue of September 3, 2009. Featured are articles on gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma, screening for epidermal growth factor receptor mutations in lung cancer, injectable collagenase clostridium histolyticum for Dupuytren's contracture, and fluvastatin in patients undergoing vascular surgery; review articles on coronary calcium screening for cardiovascular prevention and on intestinal transplantation; a Clinical Problem-Solving article desc...

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[ Wed, 2 Sep 2009 10:18:14 -0400 ]



NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 9.

This summary covers the issue of August 27, 2009. Featured are articles on exposure to low-dose ionizing radiation from medical imaging procedures, early diagnosis of myocardial infarction with sensitive cardiac troponin assays, sensitive troponin I assay in early diagnosis of acute myocardial infarction, the hypertension paradox, disclosure of financial relationships to participants in clinical research, and finding the weakness in cancer; a review article on interleukin-17 and type 17 helper ...

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[ Wed, 26 Aug 2009 10:18:14 -0400 ]



NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 8.

This summary covers the issue of August 20, 2009. Featured are articles on denosumab in men receiving androgen-deprivation therapy for prostate cancer, denosumab for prevention of fractures in postmenopausal women with osteoporosis, letrozole therapy alone or in sequence with tamoxifen in women with breast cancer, and diacetylmorphine versus methadone for the treatment of opioid addiction; review articles on infection associated with prosthetic joints and on the sudden infant death syndrome; a ...

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[ Wed, 19 Aug 2009 10:18:14 -0400 ]



NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 7.

This summary covers the issue of August 13, 2009. Featured are articles on micrometastases or isolated tumor cells and the outcome of breast cancer, weight lifting in women with breast-cancer-related lymphedema, severe respiratory disease concurrent with H1N1 influenza circulation, pneumonia and respiratory failure from swine-origin influenza A in Mexico, the premature release of data from clinical trials of ezetimibe, and luteinizing hormone and ovulation; a review article on uterine fibroid e...

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[ Wed, 12 Aug 2009 10:18:14 -0400 ]



NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 6.

This summary covers the issue of August 6, 2009. Featured are articles on vertebroplasty for osteoporotic vertebral fractures, peginterferon alfa-2b or alfa-2a with ribavirin for treatment of hepatitis C infection, apixaban or enoxaparin for thromboprophylaxis after knee replacement, and health care reform and more freedom, and responsibility, for physicians; a review article on neurologic prognosis after cardiac arrest; a Clinical Problem-Solving article describing a hard diagnosis; and Perspec...

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[ Wed, 5 Aug 2009 10:18:14 -0400 ]



NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 5.

This summary covers the issue of July 30, 2009. Featured are articles on perioperative safety in the longitudinal assessment of bariatric surgery, artemisinin-resistant Plasmodium falciparum malaria, protection against a malaria challenge by sporozoite inoculation, loss of mismatched HLA in leukemia after stem-cell transplantation, variant AGC1 and hypomyelination, and plasmodium and the platelet; a review article on psoriasis; a case report of a woman with painful swelling of the neck; and Per...

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[ Wed, 29 Jul 2009 10:18:14 -0400 ]



NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 4.

This summary covers the issue of July 23, 2009. Featured are articles on a cluster-randomized effectiveness trial of Vi typhoid vaccine in India, thrombomodulin mutations in atypical hemolytic-uremic syndrome, hearing improvement after bevacizumab in patients with neurofibromatosis type 2, effects of pay for performance on the quality of primary care in England, and a Medicare Part D update; a review article on ectopic pregnancy; a case report of a boy with headache, nausea, seizures, and hyper...

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[ Wed, 22 Jul 2009 10:18:14 -0400 ]



NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 3.

This summary covers the issue of July 16, 2009. Featured are articles on endoscopic versus open vein-graft harvesting in coronary-artery bypass surgery, genotype disclosure and Alzheimer's disease, memory loss and the APOE E4 allele, capsule endoscopy versus colonoscopy for detecting polyps and cancer, and memory and the NMDA receptors; review articles on HPV vaccination for the prevention of cervical intraepithelial neoplasia and on a historical perspective on the emergence of influenza A (H1N...

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[ Wed, 15 Jul 2009 10:18:14 -0400 ]



NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 2.

This summary covers the issue of July 9, 2009. Featured are articles on poly(ADP-ribose) polymerase inhibitor in BRCA-related cancer, raxibacumab for the treatment of inhalational anthrax, rates of serious infection after changes in regimens for medical abortion, lack of association between folate-receptor autoantibodies and neural-tube defects, an investigation of the cause of death in a gene-therapy trial, and limits on police use of bioidentifiers in Europe; a review article on screening for...

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[ Wed, 8 Jul 2009 10:18:14 -0400 ]



NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 1.

This summary covers the issue of July 2, 2009. Featured are articles on phospholipase A2 receptor in idiopathic membranous nephropathy, an epidemiologic study of in-hospital CPR in the elderly, preoperative staging of lung cancer with combined PET-CT, the effects of enalapril and losartan in type 1 diabetes, the effect of Medicare Part D on drug and medical spending, and cardiomyocyte renewal; a review article on rhabdomyolysis and acute kidney injury; a Clinical Problem-Solving article describ...

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[ Wed, 1 Jul 2009 10:18:14 -0400 ]



NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 26.

This summary covers the issue of June 25, 2009. Featured are articles on routine early angioplasty after fibrinolysis for acute myocardial infarction, mutation in ovarian granulosa-cell tumors, treating childhood acute lymphoblastic leukemia without cranial irradiation, and isolated familial hypogonadotropic hypogonadism and a GNRH1 mutation; review articles on alpha1-antitrypsin deficiency and on alcoholic hepatitis; a case report of a woman with a blistering cutaneous eruption; and Perspectiv...

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[ Wed, 24 Jun 2009 10:18:14 -0400 ]



NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 25.

This summary covers the issue of June 18, 2009. Featured are articles on the emergence of a novel swine-origin influenza A (H1N1) virus in humans, triple-reassortant swine influenza A (H1) in humans in the United States, 2005-2009, evaluation of universal antenatal screening for group B streptococcus, immunodeficiency associated with FCN3 mutation and ficolin-3 deficiency, and a new target for tumor therapy; a review article on autologous hematopoietic stem-cell transplantation for multiple mye...

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[ Wed, 17 Jun 2009 10:18:14 -0400 ]



NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 24.

This summary covers the issue of June 11, 2009. Featured are articles on treatment for type 2 diabetes and coronary artery disease, duration of androgen suppression in the treatment of prostate cancer, safety of metaclopramide use in the first trimester of pregnancy, Zika virus outbreak on Yap Island, and primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants; a review article on prenatal screening for aneuploidy; a Clinical Problem-Solving article entitled Kiss of Death; an...

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[ Wed, 10 Jun 2009 10:18:14 -0400 ]



NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 23.

This summary covers the issue of June 4, 2009. Featured are articles on diarylquinoline TMC207 for MDR tuberculosis, overseas screening for tuberculosis in U.S.-bound immigrants and refugees, canakinumab in the cryopyrin-associated periodic syndrome, an autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist, an autoinflammatory disease due to homozygous deletion of the IL1RN locus, and the granuloma in tuberculosis; a review article on immunologic aspects of COPD; a c...

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[ Wed, 3 Jun 2009 10:18:14 -0400 ]



NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 22.

This summary covers the issue of May 28, 2009. Featured are articles on radiofrequency ablation in Barrett's esophagus with dysplasia; mutation in TET2 in myeloid cancers; age, neuropathology, and dementia; inactivating PAPSS2 mutations in a patient with premature pubarche; and handguns, health, and the Second Amendment; review articles on chronic venous insufficiency and varicose veins and on predisposing factors for adrenal insufficiency; a case report of a man with progressive neurologic def...

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[ Wed, 27 May 2009 10:18:14 -0400 ]



NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 21.

This summary covers the issue of May 21, 2009. Featured are articles on early versus delayed invasive intervention in acute coronary syndromes, early glycoprotein IIb/IIIa inhibition in acute coronary syndromes, dipyridamole plus aspirin for hemodialysis graft patency, cost implications of reduced work hours and workloads for resident physicians, and mining rhinovirus sequencing; a review article on fomepizole for ethylene glycol and methanol poisoning; a case report of a pregnant woman with an...

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[ Wed, 20 May 2009 10:18:14 -0400 ]



NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 20.

This summary covers the issue of May 14, 2009. Featured are articles on adjuvant chemotherapy in older women with early-stage breast cancer, effect of clopidogrel added to aspirin in patients with atrial fibrillation, epinephrine and dexamethasone in children with bronchiolitis, antivenom for critically ill children with neurotoxicity from scorpion stings, and a fatal case of deer tick encephalitis; a review article on fungal nail disease; a case report of a man with coma after cardiac arrest; ...

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[ Wed, 13 May 2009 10:18:14 -0400 ]



NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 19.

This summary covers the issue of May 7, 2009. Featured are articles on long-term safety and efficacy of drug-eluting versus bare-metal stents in Sweden; paclitaxel-eluting stents versus bare-metal stents in acute myocardial infarction; epilepsy, ataxia, sensorineural deafness, tubulopathy, and KCNJ10 mutations; STIM1 mutation associated with a syndrome of immunodeficiency and autoimmunity; vaccine refusal and the risks of vaccine-preventable diseases; New York City's war on fat, and the origins...

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[ Wed, 6 May 2009 10:18:14 -0400 ]



NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 18.

This summary covers the issue of April 30, 2009. Featured are articles on CD4 count and antiretroviral therapy for HIV, telaprevir with peginterferon and ribavirin for chronic HCV infection, telaprevir and peginterferon with or without ribavirin for chronic HCV infection, rosuvastatin to prevent venous thromboembolism; review articles on asthma in pregnancy and on aspergillosis; a case report of a man with chest pain, dysphagia, and pleural and mediastinal calcifications; and Perspective articl...

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[ Wed, 29 Apr 2009 10:18:14 -0400 ]



NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 17.

This summary covers the issue of April 23, 2009. Featured are articles on coronary bypass surgery with or without surgical ventricular reconstruction, susceptibility locus for stroke, HTRA1 mutations and familial ischemic cerebral small-vessel disease, changes in the incidence and duration of periods without insurance, and autophagy and Crohn's disease; review articles on minimally invasive total knee arthroplasty and on understanding genetic causes of disease; a case report of a woman with res...

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[ Wed, 22 Apr 2009 10:18:14 -0400 ]


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