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The AIDS Pandemic

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Language: English
Category: Health / Medicine
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PRODUCT(RED): Philanthropy or Exploitation?
Product(RED)An earlier installment of this podcast from a year ago called attention to the launch of PRODUCT(RED) in the United States. Since the brand’s introduction, (RED) watches, sunglasses, t-shirts, cell phones, and iPods have been extensively marketed and sold, with some of the revenues going to support the fight against AIDS in Africa. Nevertheless, the (RED) brand has been a target of criticism for its commercial approach to a philanthropic endeavor. In this installment, I intend to ...

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[ Sat, 03 Nov 2007 09:34:40 -0500 ]


Integrase Inhibitors: A New Hope
I’m Bevin English.On October 12th, the Food and Drug Administration (the FDA) announced that it had approved a New Drug Application for a completely new kind of medication in the fight against AIDS. This drug, called IsentressTM, is the first integrase inhibitor and comes in 400 mg tablets that are taken twice daily. Produced by Merck & Co., Inc., Isentress, whose generic name is raltegravir and whose in-development name was MK-0518, has impressed many leading AIDS researchers, including Dr. Am...

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[ Fri, 26 Oct 2007 14:24:56 -0500 ]


Integrase Inhibitor Isentress Provides a New Way to Treat AIDS Patients
Welcome to this installment of The AIDS Pandemic, a podcast hosted by Dr. David Wessner from the Department of Biology at Davidson College. I’m Mike Neri.In this podcast, I will talk about the optimism surrounding the recently FDA approved AIDS drug Isentress, including how it works, what step in the HIV replication cycle it affects, and what preliminary data show about the drug’s effectiveness and side effects. Ever since the discovery of HIV as the causative agent of AIDS, scientists have sea...

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[ Fri, 26 Oct 2007 14:07:53 -0500 ]


HIV/AIDS: The Brazilian Response
In the arena of HIV/AIDS prevention and treatment, Brazil has become a beacon of hope, particularly among developing countries. Countries around the globe are now looking towards their system of universal AIDS care for guidance.In the early 90’s it was estimated that within a decade, the number of HIV+ people in Brazil would be near 1.2 million. Instead, recent estimates suggest that only half that amount (about 660,000 people) are infected. How have they been so successful in limiting the sp...

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[ Wed, 24 Oct 2007 20:59:04 -0500 ]


The AIDS Pandemic - Your Thoughts
Welcome to this installment of The AIDS Pandemic. I’m Dave Wessner.Last week, I was invited to speak about this blog and podcast at the annual meeting of the American Society for Virology in Corvallis Oregon. Based on questions and comments I received, I’d like to try something a little different with this installment. I’d like to ask for your opinion of this project.Before getting your feedback, though, I’d like to remind everyone about the genesis of this podcast. I began it during the summer ...

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[ Mon, 30 Jul 2007 12:53:50 -0500 ]


National HIV Testing Day
Welcome to this install of The AIDS Pandemic, a podcast hosted by Dr. David Wessner of Davidson College. I’m Dave Wessner.June 27 is the 15th annual National HIV Testing Day, an event sponsored by the National Association of People with AIDS to encourage people to get tested and learn their HIV status. Today, I had the pleasure of participating in a Webinar hosted by the Department of Health and Human Services and the Centers for Disease Control and Prevention about this important event.During t...

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[ Fri, 22 Jun 2007 13:49:20 -0500 ]


Bush advocates $30B for PEPFAR
Welcome to this installment of The AIDS Pandemic, a podcast hosted by Dr. David Wessner from Davidson College. I’m Dave Wessner.Yesterday, President Bush implored Congress to extend PEPFAR, the President’s Emergency Plan for AIDS Relief, for an additional 5 years and allocate an additional $30 billion to the program. Initially proposed in the President’s 2003 State of the Union address, PEPFAR targets HIV/AIDS treatment in 15 countries with high HIV/AIDS burdens.As President Bush noted, the $15 ...

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[ Thu, 31 May 2007 11:06:16 -0500 ]


True Colors Tour for the Human Rights Campaign
Welcome to this installment of The AIDS Pandemic, a podcast hosted by Dr. David Wessner from Davidson College. I’m Dave Wessner.We opened this installment with a short segment from True Colors, by Cyndi Lauper, the iconic voice of ‘80s pop. Long supported by and a supporter of the gay, lesbian, bisexual, and transgender communities, Lauper recently announced her plans for this summer’s True Colors tour in support of the Human Rights Campaign. Along with Debbie Harry, the Dresden Dolls, Erasure,...

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[ Fri, 18 May 2007 10:20:22 -0500 ]


Microbicides: Empowering women
Current global AIDS statistics are staggering, to say the least. Approximately 40 million people worldwide are living with the disease, while 14,000 new infections occur each day. Women make up almost 50% of adult infections, but this figure is higher in sub-Saharan Africa, where women are 30% more likely to be HIV-positive than men. Due to physiological differences, women are twice as likely as men to contract HIV from an infected partner, but many lack the necessary tools for protection. Ev...

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[ Sun, 06 May 2007 15:32:50 -0500 ]


VIRIP: A new anti-HIV compound?
Welcome to this installment of The AIDS Pandemic. I’m Dave Wessner.Could our own bodies be producing potent inhibitors of HIV? According to research published in today’s issue of Cell, the answer may be ‘Yes.’ And these interesting findings eventually may lead to the development of new anti-retroviral drugs.Since the isolation of HIV in 1983, numerous naturally occurring human factors have been postulated to have anti-HIV properties. Today, a group of researchers in Germany have added another fa...

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[ Fri, 20 Apr 2007 12:13:47 -0500 ]


Kiva: Using microfinancing to help people in developing countries
Paul Farmer, one of the founders of Partners in Health, describes the ‘great epi divide,’ the epidemiological divide that exists between developed countries and developing countries, between affluent neighborhoods and less well-off neighborhoods, between the haves and the have-nots. Morbidity and mortality associated with infectious diseases, Farmer notes, correlate well with economic disparities.HIV/AIDS is no exception. Certainly, HIV can, and does, infect people of all walks of life. Increasi...

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[ Sat, 14 Apr 2007 13:02:33 -0500 ]


Refrigeration and HIV Meds in Resource-limited Settings
I'm Charlie Raver.One of the distinguishing characteristics between the AIDS epidemic in the developed world and that in Africa and the developing world is a simple lack of the infrastructure to deal with the disease. Infrastructure includes everything from roads to electricity to hospitals. One example that most of us rarely think of as a gift, couldn’t dream of walking into a home and not finding, and would be lost without is something to which many in the developing world do not have access. ...

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[ Fri, 30 Mar 2007 14:27:53 -0500 ]


AIDS Orphans in Sub-Saharan Africa
I'm Christie BroughAccording to the AIDS Epidemic Update of December 2006, about 25 million people are living with HIV in sub-Saharan Africa, comprising 63 percent of all individuals with HIV globally. Approximately 13.3 million, or 59 percent, of these individuals are women, most of whom have children. Although considerable efforts have been made to provide these individuals increased access to antiretroviral therapy, 2.1 million Africans died in 2006, resulting in an increased number of AIDS...

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[ Fri, 23 Mar 2007 13:37:54 -0500 ]


Stigma in the Lives of HIV+ Healthcare Workers
I'm Pete Levandoski Advances in HIV related pharmacology have given HIV patients extended lifetimes, turning them from dead men walking to living individuals with a debilitating condition. In treating any patient, HIV status not withstanding, the American Dental Association states that dentists should practice, “high ethical standards which have the benefit of the patient as their primary goal” (Rhode Island Dental Association, 2006). If the maxim is adhered to, dentists should have no problem...

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[ Fri, 16 Mar 2007 14:50:35 -0500 ]


AIDS dementia: Current findings
Welcome to The AIDS Pandemic, a podcast hosted by Dr. David Wessner from the Department of Biology at Davidson College. I'm Steve Halliday.One of my most striking memories from my time spent in the hospital in Mwandi was towards the end of my stay when I saw a woman suffering from AIDS dementia who was in the courtyard screaming at the top of her lungs. I asked one of the hospital employees what was going on, and he responded “oh, she is confused.” Since that moment I’ve been interested in thi...

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[ Fri, 09 Mar 2007 09:36:22 -0600 ]


HIV/AIDS in Prisons
Welcome to this installment of the AIDS Pandemic, a podcast hosted by Dave Wessner of the Department of Biology at Davidson College. I am Justin Fried.?Prisons have become a fertile ground for the HIV epidemic in the United States. In fact the Joint United Nation Programme on AIDS (UNAIDS) listed prisoners as one of the four "major at-risk and neglected populations" in the HIV/AIDS pandemic (2006 Report on the Global AIDS Epidemic). The other three categories included men who have sex with men, ...

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[ Fri, 02 Mar 2007 13:50:15 -0600 ]


A Dual Epidemic: HIV/AIDS and Injection Drug Use in Russia
I'm Meredith Prasse.Before 1995, the total number of HIV infections in the entire region of central and Eastern Europe, with over 450 million inhabitants, was less than 30,000. The World Health Organization reported an estimated 0.6-1.9% prevalence, between 420,000 and 1.4 million cases, of HIV/AIDS in Russia in 2003. Between 1996 and 1998 alone, Russia experienced a 100-fold increase in new HIV infections, demonstrating the rapid onset of the epidemic in this region. Well over 70% of all...

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[ Fri, 23 Feb 2007 13:21:17 -0600 ]


Male Circumcision and HIV/AIDS
“When is it appropriate for public health practice to be on the side of an intervention that causes bodily injury?” (Franco)I'm Erika Larson.That is the question McGill’s Professor of Epidemiology, Eduardo Franco, asked when addressing circumcision as a possible method of reducing HIV prevalence. Circumcision has historically caused a polarizing debate across sectors of society including the pious, and the hygienic. Health workers have generally abstained from taking a side. However, new evide...

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[ Fri, 16 Feb 2007 09:13:48 -0600 ]


The Links between HIV/AIDS and National Security
I'm Rebecca Jameson In July of 2000, the UN Security Council passed Resolution 1308 stipulating that HIV poses a risk to the stability and security of the nations of the world. Since then, there has been considerable debate regarding the relationship between the AIDS pandemic and national security. According to expert analysts, the security implications of HIV’s rapid spread in Africa and other regions must be taken far more seriously by the industrialized West. One concern expressed by security...

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[ Sat, 03 Feb 2007 15:42:38 -0600 ]


History of HIV/AIDS in the United States
In a speech given on December 1, 2006, World AIDS Day, Kofi Annan declared HIV/AIDS to be the greatest challenge of our generation. This dreaded infectious disease has claimed the lives of over 25 million people worldwide and infected 40 million more. In the United States alone, 1.2 million are infected with the HIV virus and more than 500,000 have died. No virus has been as well studied or understood as the human immunodeficiency virus, yet we are far from controlling this pandemic.When th...

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[ Fri, 02 Feb 2007 11:43:13 -0600 ]


Pre-exposure Chemoprophylaxis
Leaders from around the world in AIDS research and health policy gathered in Toronto in August 2006 for the XVI International AIDS Conference. A key theme of the conference was HIV prevention, including assessment of old standards as well as new strategies. Leigh Peterson of Family Health International presented preliminary data from a current AIDS prevention study of women in Ghana (2006). This new prevention strategy is called pre-exposure chemoprophylaxis, or PrEP. In the PrEP strategy, HIV-n...

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[ Tue, 30 Jan 2007 15:25:19 -0600 ]


Considerations for Real-World Use of Microbicides
For more than ten years, the scientific community has been touting microbicides as the next big breakthrough in HIV/AIDS prevention. Microbicides are compounds that protect against sexually transmitted infections such as HIV and can be applied inside the vagina or rectum as a gel, cream, film, or suppository. Numerous strategies for microbicides are currently in development, including disruption of HIV’s viral envelope, maintenance of the normally acidic environment of the vagina, nonspecific ...

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[ Fri, 19 Jan 2007 12:51:00 -0600 ]


Considerations for Real-World Use of Microbicides
For more than ten years, the scientific community has been touting microbicides as the next big breakthrough in HIV/AIDS prevention. Microbicides are compounds that protect against sexually transmitted infections such as HIV and can be applied inside the vagina or rectum as a gel, cream, film, or suppository. Numerous strategies for microbicides are currently in development, including disruption of HIV’s viral envelope, maintenance of the normally acidic environment of the vagina, nonspecific ...

MORE... | LISTEN | DOWNLOAD | MOBILE DEVICE

[ Fri, 19 Jan 2007 12:51:00 -0600 ]


The AIDS Pandemic: A note to our listeners
Our podcast is now 6 months old. During this time, we have addressed many topics related to HIV/AIDS, including recent advances in treatment, the South African disability grant program, HIV in the Southeastern United States, and Bono’s Product (RED) campaign. If you are a regular listener, you probably know that many of the episodes have been conceived, developed, and produced by Davidson College undergraduate students. Rebecca Jameson, a senior at Davidson, discussed violence toward women and ...

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[ Thu, 11 Jan 2007 12:53:00 -0600 ]


The AIDS Pandemic: A note to our listeners
Our podcast is now 6 months old. During this time, we have addressed many topics related to HIV/AIDS, including recent advances in treatment, the South African disability grant program, HIV in the Southeastern United States, and Bono’s Product (RED) campaign. If you are a regular listener, you probably know that many of the episodes have been conceived, developed, and produced by Davidson College undergraduate students. Rebecca Jameson, a senior at Davidson, discussed violence toward women and ...

MORE... | LISTEN | DOWNLOAD | MOBILE DEVICE

[ Thu, 11 Jan 2007 12:53:00 -0600 ]


HIV/AIDS Stigma in Rural America
One of the largest obstacles to proper care of patients early in the AIDS epidemic was and may still be stigma associated with the disease. A common question throughout any major crisis and especially the AIDS epidemic is how the reaction in urbanized America differs from the more rural parts of the United States. To gain some insight into these issues, I have asked my parents to share their first experiences with AIDS patients and their thoughts on these issues. My father, Dr. James Raver, is a...

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[ Tue, 26 Dec 2006 16:38:00 -0600 ]


HIV/AIDS Stigma in Rural America
One of the largest obstacles to proper care of patients early in the AIDS epidemic was and may still be stigma associated with the disease. A common question throughout any major crisis and especially the AIDS epidemic is how the reaction in urbanized America differs from the more rural parts of the United States. To gain some insight into these issues, I have asked my parents to share their first experiences with AIDS patients and their thoughts on these issues. My father, Dr. James Raver, is a...

MORE... | LISTEN | DOWNLOAD | MOBILE DEVICE

[ Tue, 26 Dec 2006 16:38:00 -0600 ]


Side effects of HAART
Welcome to this installment of the AIDS Pandemic, a podcast hosted by Dave Wessner of the Department of Biology at Davidson College. I am Justin Fried.A study recently published in the Journal of Infectious Diseases credited AIDS treatment for saving 3,000,000 years of life in the United States (Walensky et al 2006). While effective treatment of common AIDS-related opportunistic infections has indeed benefited AIDS patients, the study cites treatments that decrease the virulence of the HIV virus...

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[ Wed, 13 Dec 2006 14:54:00 -0600 ]


Side effects of HAART
Welcome to this installment of the AIDS Pandemic, a podcast hosted by Dave Wessner of the Department of Biology at Davidson College. I am Justin Fried. A study recently published in the Journal of Infectious Diseases credited AIDS treatment for saving 3,000,000 years of life in the United States (Walensky et al 2006). While effective treatment of common AIDS-related opportunistic infections has indeed benefited AIDS patients, the study cites treatments that decrease the virulence of the HIV vir...

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[ Wed, 13 Dec 2006 14:54:00 -0600 ]


Selective Pressures on CCR5-?32 in the European Population
I'm Pete Levandoski Recent research into the HIV pandemic has focused on the presence of individuals who do not become infected by HIV when exposed to the virus. So-called co receptors, which are essential for viral docking and infection, are thought to play a role in this immunity. One such co receptor is the protein CCR5, a chemokine receptor on the surface of T4 cells (Galvani et al.). Individuals who lack functional CCR5 protein do not become infected when exposed to HIV-1. A gene mutation, ...

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[ Mon, 11 Dec 2006 08:59:00 -0600 ]

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